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Renee Haskew-Layton

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  4. Renee Haskew-Layton
Assistant Professor, Natural Science
School of Health and Natural Sciences

Research Interests

Image above: Green: neurons; Red: astrocytes. Astrocytes play an important role in protecting neurons from oxidative stress.

Many of us are familiar with the idea that free radicals are damaging to the body and that antioxidants protect us against these free radicals. In fact, our bodies are constantly producing reactive oxygen species (ROS - reactive molecules that include free radicals) as byproducts of metabolism. While low levels of ROS are important for the noraml function of our bodies, ROS accumulation beyond a redox homeostatic setpoint may damage our cells. Antioxidants are part of a checks and balances system that help keep ROS levels low, thus allowing our bodies to maintain redox homeostasis.

My research focuses on leveraging antioxidant sources in the brain as a way to limit neuronal death in neurodegenerative diseases (eg. Alzheimer Disease, Parkinson Disease, Huntington Disease, ALS) and neurological disorders (eg. stroke, spinal cord injury, traumatic brain injury). I have a particular interest in understanding how the glial cell type, the astrocyte, helps maintain a healthy brain by combatting oxidative stress. In addition to playing numerous roles in the brain - such as facilitating neuronal communication and supplying growth factors to neurons - astrocytes are also a rich source of antioxidants. When neurons encounter oxidative stress, astrocytes increase the production of antioxidant molecules via the transcription factor Nrf2. Together with a group of Mercy College undergraduate students, I study both Nrf2-dependent and Nrf2-independent neuroprotection involving astrocytes.

Classes Taught

BIOL 366 Developmental Biology, BIOL 160 General Biology I Lecture, CHEM 160 General Chemistry I Lecture, BIOL 317 Clinical Neuroscience, BIOL 355 Molecular Biol of the Cell, BIOL 295 Research in Biology I.

Education

Albany Medical College

Ph.D. Neuropharmacology and Neuroscience

University at Albany (SUNY Albany)

B.A. Psychology with Biology concentration

CV

  • Postdoctoral Fellow

    Burke Medical Research Institute of Weill Cornell Medical College

    2005 - 2011
  • Adjunct Associate Professor

    Pace University

    2011 - 2014
  • Visiting Assistant Professor

    Mercy College

    2014 - 2015
  • Assistant Professor and Program Director of Biology

    Mercy College

    2015 - Present

Articles

PDF icon Haskew-Layton Publications.pdf
Contact Information
Main Hall 300
555 Broadway
Dobbs Ferry
NY
10522
914-674-7145
rhaskewlayton@mercy.edu

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